Estrogen and Tobacco Smoke

Scientists at Fox Chase Cancer Center in Philadelphia say that estrogen is metabolized into toxic derivatives in the mouse lung and the levels of these toxic metabolites increased when mice were exposed to tobacco smoke. These researchers are looking into methods to prevent estrogen from being converted into toxins and they hope that the methods could be applied to lung cancer treatments someday. Jing Peng (PhD) says, "In the future, we would like to target estrogen-metabolizing pathways as a form of treatment or prevention of lung cancer." Peng and colleagues hope that therapies targeting estrogen metabolism can be used as a way to treat or prevent lung cancer. They also would like to reiterate the detriments of choosing to smoke tobacco and encourage people to live a healthy lifestyle that does not include inhaling tobacco smoke. http://www.sciencedaily.com/releases/2012/04/120403193832.html