A study has shown that overeating may cause brain again while eating less turns on a molecule that helps the brain stay young. A team of researchers at the Catholic University of Sacred Heart in Rome discovered a molecule called CREB1, which is triggered by low calorie intake in mice( they think it happens in humans to, but no test have been done yet). They found that CREB1 activates many genes linked to longevity and to the proper functioning of the brain.
http://medicalxpress.com/news/2011-12-brain-young.html

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