Finding by UCI team could help prevent cardiovascular complications

 UC Irvine researchers have uncovered an important source of inflammation seen in people with chronic kidney disease, which is increasingly common due to the epidemic of obesity-related diabetes and hypertension.Dr. N.D. Vazir of UC Irvine found that,"CKD causes massive depletion of the key adhesive proteins, called the tight junction, that normally seal the space between the cells lining the intestines. This breakdown in the colon allows the leakage of microbial products and other noxious material into the body’s internal environment, accounting for the persistent systemic inflammation that frequently occurs in CKD patients."

http://www.healthcanal.com/kidneys-urinary-system/24548-Major-cause-chronic-kidney-disease-related-inflammation-identified.html