Chemists at Brown University have successfully used a new and highly efficient method to create a compound that makes previously drug-resistant bacteria vulnerable to antibiotics once again. Named BU-005, it works by blocking pumps that certain bacteria utilize to remove antibacterial agents from their cell structure. The compound will be effective in many strains of bacteria, including MRSA and tuberculosis. These scientists' work could open the door to a slew of new dipeptide efflux-pump-blocker discoveries, which would greatly aid in the constant struggle against antibiotic resistance. Their new methods have made the process of creating these blockers much quicker.
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